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Sildenafil can be a potent and selective inhibitor of cGMP unique phosphodiesterase kind 5 (PDE5) inside the corpus cavernosum, in which PDE5 is to blame for degradation of cGMP. Sildenafil contains a peripheral web page of action on erections. Sildenafil has no direct relaxant impact on isolated human corpus cavernosum but potently boosts the rela